Saturday, February 21, 2026

I took the shot

 

 

Leqvio.  It’s to reduce LDL cholesterol.

 

Cardiovascular issues.  Statin intolerance.  Elevated LDL cholesterol numbers; not way out of range, but elevated.  Advice for all these years to lower my LDL numbers.  But no solution that’s not worse than the problem.

 

If the physician documents a person as intolerant of other medications, or other medications don’t work, that person can be cleared for Repatha or Leqvio.  They are both shots instead of pills.  Repatha you give yourself a shot every two weeks.  Years ago, after I got my heart surgery, I got cleared to use it.  I didn’t have a problem with injecting myself every two weeks, but I never pulled the trigger.  I had this reservation about messing with a machine so complicated and effective as the human body, and throwing it out of balance, creating more and different problems.  Unintended consequences from trying to go from good to better.  Risky.

 

Now, years later, we’re still having the same conversation about lowering LDL cholesterol and the numbers continue to climb a bit.  So we’ll give it a go.  With Leqvio, instead of an injection every two weeks, it’s an injection twice a year, administered at a clinic.  Got the shot on Tuesday.  Felt crummy for the rest of the day.  Not an unusual reaction to the shot.  Wednesday and after, I’m feeling just fine.

 

I think two weeks will be the key.  Every other medicine I’ve tried to lower cholesterol, I’ve reacted within two weeks.  From my experience I conclude that either I just can’t tolerate the particular drugs, or I can’t tolerate being without the amount of cholesterol my body normally produces.  Don’t know which is it.

 

I think we’ll know soon enough.

 

 

 

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